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Structure paper

TitleEukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge.
Journal, issue, pagesNat Commun, Vol. 15, Page 6104-6104, Year 2024
Publish dateDec 4, 2023 (structure data deposition date)
AuthorsHong, Z. / Byrd, A.K. / Gao, J. / Das, P. / Tan, V.Q. / Malone, E.G. / Osei, B. / Marecki, J.C. / Protacio, R.U. / Wahls, W.P. ...Hong, Z. / Byrd, A.K. / Gao, J. / Das, P. / Tan, V.Q. / Malone, E.G. / Osei, B. / Marecki, J.C. / Protacio, R.U. / Wahls, W.P. / Raney, K.D. / Song, H.
External linksNat Commun / PubMed:39030241
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-8xak:
Structure of Pif1-G4 complex
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / Pif1 / HYDROLASE / HYDROLASE-DNA complex

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