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TitleALS mutations disrupt self-association between the Ubiquilin Sti1 hydrophobic groove and internal placeholder sequences.
Journal, issue, pagesBiorxiv, Year 2025
Publish dateJul 10, 2024 (structure data deposition date)
AuthorsOnwunma, J. / Binsabaan, S. / Allen, S.P. / Sankaran, B. / Wohlever, M.L.
External linksBiorxiv / PubMed:39026758
MethodsX-ray diffraction
Resolution1.98 Å
Structure data

PDB-9ckx:
Crystal structure of Dsk2 Sti1 domain bound to a transmembrane domain
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • metschnikowia bicuspidata (fungus)
  • myxococcus xanthus (bacteria)
  • homo sapiens (human)
KeywordsCHAPERONE / Membrane protein Chaperone Sti1 Ubiquilin

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