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Structure paper

TitleA vitamin D-based strategy overcomes chemoresistance in prostate cancer.
Journal, issue, pagesBr. J. Pharmacol., Vol. 181, Page 4279-4293, Year 2024
Publish dateJun 6, 2023 (structure data deposition date)
AuthorsLen-Tayon, K. / Beraud, C. / Fauveau, C. / Belorusova, A.Y. / Chebaro, Y. / Mourino, A. / Massfelder, T. / Chauchereau, A. / Metzger, D. / Rochel, N. / Laverny, G.
External linksBr. J. Pharmacol. / PubMed:38982588
MethodsX-ray diffraction
Resolution2.15 - 2.9 Å
Structure data

PDB-8p9w:
vitamin D receptor complex with Xe4MeCF3 analog
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-8p9x:
Vitamin D receptor complex with Xe4Me agonist ligand
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals


ChemComp, No image

ChemComp-XDO:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION


ChemComp, No image

ChemComp-FO6:
Unknown entry

Source
  • danio rerio (zebrafish)
  • homo sapiens (human)
KeywordsTRANSCRIPTION / nuclear receptor / agonist / ligand binding domain

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