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-Structure paper
Title | An antibody that inhibits TGF-beta 1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis. |
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Journal, issue, pages | Sci. Signal., Vol. 17, Page eadn6052-eadn6052, Year 2024 |
Publish date | Sep 29, 2023 (structure data deposition date) |
Authors | Jackson, J.W. / Streich Jr., F.C. / Pal, A. / Coricor, G. / Boston, C. / Brueckner, C.T. / Canonico, K. / Chapron, C. / Cote, S. / Dagbay, K.B. ...Jackson, J.W. / Streich Jr., F.C. / Pal, A. / Coricor, G. / Boston, C. / Brueckner, C.T. / Canonico, K. / Chapron, C. / Cote, S. / Dagbay, K.B. / Danehy Jr., F.T. / Kavosi, M. / Kumar, S. / Lin, S. / Littlefield, C. / Looby, K. / Manohar, R. / Martin, C.J. / Wood, M. / Zawadzka, A. / Wawersik, S. / Nicholls, S.B. / Datta, A. / Buckler, A. / Schurpf, T. / Carven, G.J. / Qatanani, M. / Fogel, A.I. |
External links | Sci. Signal. / PubMed:38980922 |
Methods | X-ray diffraction |
Resolution | 2.21 Å |
Structure data | PDB-8udz: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/IMMUNE SYSTEM / Growth factor / antibody / fibrosis / TGFbeta / SIGNALING PROTEIN / SIGNALING PROTEIN-IMMUNE SYSTEM complex |