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TitleHuman milk oligosaccharide 2'-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site.
Journal, issue, pagesJ. Virol., Vol. 98, Page e0086524-e0086524, Year 2024
Publish dateFeb 1, 2024 (structure data deposition date)
AuthorsRudd, P.A. / Kher, G. / Tame, J.R.H. / Irie, H. / Haselhorst, T. / von Itzstein, M. / Pancera, M. / Hansman, G.S.
External linksJ. Virol. / PubMed:38953656
MethodsX-ray diffraction
Resolution1.41 - 1.54 Å
Structure data

PDB-8y5v:
GII.4 Sydney PD and 2'-FL
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-8y6c:
Norovirus GII.10 P domain and 2'-FL (powder)
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

PDB-8y6d:
Norovirus GII.10 P domain and 2'-FL (tablet)
Method: X-RAY DIFFRACTION / Resolution: 1.41 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NO3:
NITRATE ION

Source
  • norovirus
KeywordsVIRAL PROTEIN / Sugar / complex / milk oligosaccharide

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