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TitleMechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII.
Journal, issue, pagesAdv Sci, Vol. 11, Page e2403494-e2403494, Year 2024
Publish dateJan 9, 2023 (structure data deposition date)
AuthorsHou, X. / Feng, J. / Franklin, J.L. / Russo, R. / Guo, Z. / Zhou, J. / Gao, J.M. / Liu, H.W. / Wang, B.
External linksAdv Sci / PubMed:38943270
MethodsX-ray diffraction
Resolution2.03978804974 - 2.33001676063 Å
Structure data

PDB-8hzv:
The crystal structure of a Radical SAM Enzyme DesII
Method: X-RAY DIFFRACTION / Resolution: 2.33001676063 Å

PDB-8hzy:
The crystal structure of a Radical SAM Enzyme DesII
Method: X-RAY DIFFRACTION / Resolution: 2.03978804974 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-MET:
METHIONINE

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBIOSYNTHETIC PROTEIN / Radical S-Adenosyl-L-methionine Enzyme / Deamination / Dehydrogenase

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