+Search query
-Structure paper
Title | Spiro-Azetidine Oxindoles as Long-Acting Injectables for Pre-Exposure Prophylaxis against Respiratory Syncytial Virus Infections. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 67, Page 10986-11002, Year 2024 |
Publish date | Apr 25, 2024 (structure data deposition date) |
Authors | Kesteleyn, B. / Herschke, F. / Darville, N. / Stoops, B. / Jacobs, T. / Jacoby, E. / Shaffer, P. / Lammens, L. / Van Rompaey, D. / Matcha, K. ...Kesteleyn, B. / Herschke, F. / Darville, N. / Stoops, B. / Jacobs, T. / Jacoby, E. / Shaffer, P. / Lammens, L. / Van Rompaey, D. / Matcha, K. / Martinez Lamenca, C. / Coesemans, E. / Hache, G. / Pieters, S. / Lecomte, M. / Hu, L. / Demin, S. / Milligan, C. / Abeywickrema, P. / De Bruyn, S. / Van Den Berg, J. / Ysebaert, N. / De Zwart, L. / Najera, I. / Rigaux, P. / Roymans, D. / Jonckers, T.H.M. |
External links | J. Med. Chem. / PubMed:38932487 |
Methods | X-ray diffraction |
Resolution | 2.07 Å |
Structure data | PDB-9bjm: |
Chemicals | PDB-1apz: ChemComp-HOH: |
Source |
|
Keywords | VIRAL PROTEIN/INHIBITOR / Inhibitor / Viral Protein / Complex / VIRAL PROTEIN-INHIBITOR complex |