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TitleStructural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623.
Journal, issue, pagesInt J Mol Sci, Vol. 25, Year 2024
Publish dateNov 30, 2023 (structure data deposition date)
AuthorsSharrock, A.V. / Mumm, J.S. / Williams, E.M. / Cenas, N. / Smaill, J.B. / Patterson, A.V. / Ackerley, D.F. / Bagdziunas, G. / Arcus, V.L.
External linksInt J Mol Sci / PubMed:38928299
MethodsX-ray diffraction
Resolution1.98 Å
Structure data

PDB-8v5b:
Structure of the oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB_Ec F70A/F108Y in complex with FMN
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ACT:
ACETATE ION

ChemComp-P4K:
polyethylene glycol

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / nitroreductase / flavoprotein / FMN

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