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TitlePeripheral positions encode transport specificity in the small multidrug resistance exporters.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 121, Page e2403273121-e2403273121, Year 2024
Publish dateFeb 6, 2024 (structure data deposition date)
AuthorsBurata, O.E. / O'Donnell, E. / Hyun, J. / Lucero, R.M. / Thomas, J.E. / Gibbs, E.M. / Reacher, I. / Carney, N.A. / Stockbridge, R.B.
External linksProc. Natl. Acad. Sci. USA / PubMed:38865266
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-8vxu:
Crystal structure of Gdx-Clo A60T from Small Multidrug Resistance family of transporters in complex with cetyltrimetylammonium
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-16A:
CETYL-TRIMETHYL-AMMONIUM

Source
  • clostridia bacterium (bacteria)
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Small Multidrug Resistance / SMR / quaternary ammonium

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