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-Structure paper
Title | Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. |
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Journal, issue, pages | Cell Death Dis, Vol. 15, Page 408-408, Year 2024 |
Publish date | Oct 19, 2023 (structure data deposition date) |
![]() | Balourdas, D.I. / Markl, A.M. / Kramer, A. / Settanni, G. / Joerger, A.C. |
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Methods | X-ray diffraction |
Resolution | 1.38 - 2.1 Å |
Structure data | ![]() PDB-8qwk: ![]() PDB-8qwl: ![]() PDB-8qwm: ![]() PDB-8qwn: ![]() PDB-8qwo: ![]() PDB-8qwp: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-MLI: ![]() ChemComp-TLA: ![]() ChemComp-MG: ![]() ChemComp-CL: ![]() ChemComp-GOL: |
Source |
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![]() | DNA BINDING PROTEIN / tumor suppressor / transcription factor / cancer mutation / protein stability / conformational mutant |