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-Structure paper
Title | Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. |
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Journal, issue, pages | Nat. Chem. Biol., Year 2024 |
Publish date | Jun 21, 2023 (structure data deposition date) |
![]() | Petruzzella, A. / Bruand, M. / Santamaria-Martinez, A. / Katanayeva, N. / Reymond, L. / Wehrle, S. / Georgeon, S. / Inel, D. / van Dalen, F.J. / Viertl, D. ...Petruzzella, A. / Bruand, M. / Santamaria-Martinez, A. / Katanayeva, N. / Reymond, L. / Wehrle, S. / Georgeon, S. / Inel, D. / van Dalen, F.J. / Viertl, D. / Lau, K. / Pojer, F. / Schottelius, M. / Zoete, V. / Verdoes, M. / Arber, C. / Correia, B.E. / Oricchio, E. |
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Methods | X-ray diffraction |
Resolution | 1.56 - 1.73 Å |
Structure data | ![]() PDB-8pi3: ![]() PDB-8rnd: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-GOL: ![]() ChemComp-EDO: ![]() ChemComp-CD: ![]() ChemComp-ACT: ![]() ChemComp-PEG: ![]() ChemComp-HOH: ![]() ChemComp-PGE: ![]() ChemComp-NO3: |
Source |
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![]() | ONCOPROTEIN / Protease / Inhibitor / Complex / Cathepsin |