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TitleThe NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif.
Journal, issue, pagesCell Death Dis, Vol. 15, Page 335-335, Year 2024
Publish dateNov 14, 2023 (structure data deposition date)
AuthorsHuang, X. / Zhang, C. / Shang, X. / Chen, Y. / Xiao, Q. / Wei, Z. / Wang, G. / Zhen, X. / Xu, G. / Min, J. ...Huang, X. / Zhang, C. / Shang, X. / Chen, Y. / Xiao, Q. / Wei, Z. / Wang, G. / Zhen, X. / Xu, G. / Min, J. / Shen, S. / Liu, Y.
External linksCell Death Dis / PubMed:38744853
MethodsX-ray diffraction
Resolution1.76 - 1.87 Å
Structure data

PDB-8x3r:
Crystal structure of human WDR5 in complex with WDR5
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-8x3s:
Crystal structure of human WDR5 in complex with PTEN
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / epigenetics / cell proliferation / CELL CYCLE / Complex / Cancer

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