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TitleIntramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Journal, issue, pagesNat Commun, Vol. 15, Page 3888-3888, Year 2024
Publish dateJul 24, 2023 (structure data deposition date)
AuthorsMartinez-Lumbreras, S. / Trager, L.K. / Mulorz, M.M. / Payr, M. / Dikaya, V. / Hipp, C. / Konig, J. / Sattler, M.
External linksNat Commun / PubMed:38719828
MethodsNMR (solution)
Structure data

PDB-8pxw:
Structure of the WW domain tandem of PRPF40A
Method: SOLUTION NMR

PDB-8pxx:
Structure of the WW domain tandem of PRPF40A in complex with SF1
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsSPLICING / Dynamic WW domain tandem / Proline binding domain / Alternative Splicing Regulation / E complex / WW domain tandem / Proline-rich peptide

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