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TitleSynthesis and Evaluation of diaryl ether modulators of the leukotriene A 4 hydrolase aminopeptidase activity.
Journal, issue, pagesEur. J. Med. Chem., Vol. 272, Page 116459-116459, Year 2024
Publish dateAug 21, 2023 (structure data deposition date)
AuthorsPetruncio, G. / Lee, K.H. / Girgis, M. / Shellnutt, Z. / Beaulac, Z. / Xiang, J. / Lee, S.H. / Peng, X. / Burdick, M. / Noble, S.M. ...Petruncio, G. / Lee, K.H. / Girgis, M. / Shellnutt, Z. / Beaulac, Z. / Xiang, J. / Lee, S.H. / Peng, X. / Burdick, M. / Noble, S.M. / Shim, Y.M. / Paige, M.
External linksEur. J. Med. Chem. / PubMed:38704942
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-8twx:
Synthesis and Evaluation of Diaryl Ether Modulators of the Leukotriene A4 Hydrolase Aminopeptidase Activity
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals


ChemComp, No image

ChemComp-VI7:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Leukotriene A4 hydrolase / 4MDM / Aminipeptidase / Activator

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