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Structure paper

TitleCrystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Journal, issue, pagesEur J Cell Biol, Vol. 103, Page 151414-151414, Year 2024
Publish dateJan 12, 2024 (structure data deposition date)
AuthorsGebregiworgis, T. / Chan, J.Y. / Kuntz, D.A. / Prive, G.G. / Marshall, C.B. / Ikura, M.
External linksEur J Cell Biol / PubMed:38640594
MethodsX-ray diffraction
Resolution1.74 Å
Structure data

PDB-8vm2:
Crystal Structure of NRAS Q61K bound to GTP
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/ONCOPROTEIN / NRAS / oncogenic mutation / RAS superfamily small GTPases / HYDROLASE / HYDROLASE-ONCOPROTEIN complex

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