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TitleStaphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.
Journal, issue, pagesElife, Vol. 13, Year 2024
Publish dateAug 14, 2022 (structure data deposition date)
AuthorsSacco, M.D. / Hammond, L.R. / Noor, R.E. / Bhattacharya, D. / McKnight, L.J. / Madsen, J.J. / Zhang, X. / Butler, S.G. / Kemp, M.T. / Jaskolka-Brown, A.C. ...Sacco, M.D. / Hammond, L.R. / Noor, R.E. / Bhattacharya, D. / McKnight, L.J. / Madsen, J.J. / Zhang, X. / Butler, S.G. / Kemp, M.T. / Jaskolka-Brown, A.C. / Khan, S.J. / Gelis, I. / Eswara, P. / Chen, Y.
External linksElife / PubMed:38639993
MethodsX-ray diffraction
Resolution1.95 - 2.4 Å
Structure data

PDB-8e2b:
N-terminal domain of S. aureus GpsB
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-8e2c:
N-terminal domain of S. aureus GpsB in complex with PBP4 fragment
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus subsp. aureus col (bacteria)
KeywordsPEPTIDE BINDING PROTEIN / Peptidoglycan / PBP / PBP4 / MRSA / GpsB / PBP2a cell wall / transpeptidase / b-lactam / gram-positive / sporulation / cell division / bacterial cell division / diviva / divisome

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