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-Structure paper
Title | Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models. |
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Journal, issue, pages | Prostate, Vol. 84, Page 909-921, Year 2024 |
Publish date | Jun 30, 2024 (structure data deposition date) |
Authors | Jasmine, S. / Mandl, A. / Krueger, T.E.G. / Dalrymple, S.L. / Antony, L. / Dias, J. / Celatka, C.A. / Tapper, A.E. / Kleppe, M. / Kanayama, M. ...Jasmine, S. / Mandl, A. / Krueger, T.E.G. / Dalrymple, S.L. / Antony, L. / Dias, J. / Celatka, C.A. / Tapper, A.E. / Kleppe, M. / Kanayama, M. / Jing, Y. / Speranzini, V. / Wang, Y.Z. / Luo, J. / Trock, B.J. / Denmeade, S.R. / Carducci, M.A. / Mattevi, A. / Rienhoff, H.Y. / Isaacs, J.T. / Brennen, W.N. |
External links | Prostate / PubMed:38619005 |
Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | PDB-9fwg: |
Chemicals |
PDB-1ig2: Unknown entry |
Source |
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Keywords | OXIDOREDUCTASE / bomedemstat / epigenetics / histone demethylase |