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-Structure paper
| Title | One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 15, Page 3199-3199, Year 2024 |
| Publish date | Jul 17, 2023 (structure data deposition date) |
Authors | Malatesta, M. / Fornasier, E. / Di Salvo, M.L. / Tramonti, A. / Zangelmi, E. / Peracchi, A. / Secchi, A. / Polverini, E. / Giachin, G. / Battistutta, R. ...Malatesta, M. / Fornasier, E. / Di Salvo, M.L. / Tramonti, A. / Zangelmi, E. / Peracchi, A. / Secchi, A. / Polverini, E. / Giachin, G. / Battistutta, R. / Contestabile, R. / Percudani, R. |
External links | Nat Commun / PubMed:38615009 |
| Methods | X-ray diffraction |
| Resolution | 2.26 - 2.6 Å |
| Structure data | ![]() PDB-8pum: ![]() PDB-8pus: |
| Chemicals | ![]() ChemComp-NA: ![]() ChemComp-HOH: |
| Source |
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Keywords | LYASE / amino acid metabolic process / threonine aldolase / hydroxy trimethyl-lysine aldolase / carnitine biosynthesis / PLP-dependent enzyme |
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