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Structure paper

TitleBiochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1.
Journal, issue, pagesChem. Biol. Interact., Page 110993-110993, Year 2024
Publish dateNov 19, 2019 (structure data deposition date)
AuthorsKorasick, D.A. / Buckley, D.P. / Palpacelli, A. / Cursio, I. / Cesaroni, E. / Cheng, J. / Tanner, J.J.
External linksChem. Biol. Interact. / PubMed:38604394
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-6v0z:
Structure of ALDH7A1 mutant R441C complexed with NAD
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / ALDEHYDE DEHYDROGENASE / NAD / LYSINE CATABOLISM

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