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TitleStructure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors.
Journal, issue, pagesPlos One, Vol. 19, Page e0296995-e0296995, Year 2024
Publish dateSep 13, 2023 (structure data deposition date)
AuthorsBobrovs, R. / Bolsakova, J. / Buitrago, J.A.R. / Varaceva, L. / Skvorcova, M. / Kanepe, I. / Rudnickiha, A. / Parisini, E. / Jirgensons, A.
External linksPlos One / PubMed:38558084
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-8qic:
Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals


ChemComp, No image

ChemComp-VL0:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli o8 (bacteria)
KeywordsLIGASE / threonyl tRNA-synthetase / malaria / Plasmodium falciparum / salicylic acid

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