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TitleMouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
Journal, issue, pagesJ. Biol. Chem., Vol. 300, Page 107229-107229, Year 2024
Publish dateFeb 11, 2024 (structure data deposition date)
AuthorsCiacchi, L. / Mak, J.Y.W. / Le, J.P. / Fairlie, D.P. / McCluskey, J. / Corbett, A.J. / Rossjohn, J. / Awad, W.
External linksJ. Biol. Chem. / PubMed:38537698
MethodsX-ray diffraction
Resolution3.4 - 3.45 Å
Structure data

PDB-8vz8:
Crystal structure of mouse MAIT M2B TCR-MR1-5-OP-RU complex
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

PDB-8vz9:
Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-2LJ:
1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Mouse MAIT TCR recognition of MR1

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