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TitleInhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification.
Journal, issue, pagesProtein Sci., Vol. 33, Page e4938-e4938, Year 2024
Publish dateOct 31, 2022 (structure data deposition date)
AuthorsKrzysiak, T.C. / Choi, Y.J. / Kim, Y.J. / Yang, Y. / DeHaven, C. / Thompson, L. / Ponticelli, R. / Mermigos, M.M. / Thomas, L. / Marquez, A. ...Krzysiak, T.C. / Choi, Y.J. / Kim, Y.J. / Yang, Y. / DeHaven, C. / Thompson, L. / Ponticelli, R. / Mermigos, M.M. / Thomas, L. / Marquez, A. / Sipula, I. / Kemper, J.K. / Jurczak, M. / Thomas, G. / Gronenborn, A.M.
External linksProtein Sci. / PubMed:38533551
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-8ez6:
The DBC1/SIRT1 Interaction is Choreographed by Post-translational Modification
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / DBC1 / S1-like / insulin signaling / liver metabolism / chaperone

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