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TitleMinimising the payload solvent exposed hydrophobic surface area optimises the antibody-drug conjugate properties.
Journal, issue, pagesRsc Med Chem, Vol. 15, Page 832-838, Year 2024
Publish dateJan 10, 2024 (structure data deposition date)
AuthorsHobson, A.D. / Zhu, H. / Qiu, W. / Judge, R.A. / Longenecker, K.
External linksRsc Med Chem / PubMed:38516584
MethodsX-ray diffraction
Resolution2.133 Å
Structure data

PDB-8vkz:
Crystal structure of Glucocorticoid Receptor in complex with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.133 Å

Chemicals


PDB Unreleased entry

PDB-1ace: Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/INHIBITOR / Glucocorticord Receptor / modulator / TRANSCRIPTION / TRANSCRIPTION-INHIBITOR complex

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