+Search query
-Structure paper
Title | Restricted Rotational Flexibility of the C5 alpha-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase. |
---|---|
Journal, issue, pages | Acs Infect Dis., Vol. 10, Page 1232-1249, Year 2024 |
Publish date | Dec 8, 2023 (structure data deposition date) |
![]() | Stewart, N.K. / Toth, M. / Quan, P. / Beer, M. / Buynak, J.D. / Smith, C.A. / Vakulenko, S.B. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.62 Å |
Structure data | ![]() PDB-8v9g: ![]() PDB-8v9h: |
Chemicals | ![]() ChemComp-MER: ![]() ChemComp-EDO: ![]() ChemComp-IOD: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-Y33: ![]() ChemComp-CA: ![]() ChemComp-CL: |
Source |
|
![]() | HYDROLASE / class A beta-lactamase / carbapenemase / meropenem / antibiotic resistance |