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-Structure paper
Title | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 269, Page 116310-116310, Year 2024 |
Publish date | Dec 29, 2023 (structure data deposition date) |
![]() | Qiu, X. / Liu, R. / Ling, H. / Zhou, Y. / Ren, X. / Zhou, F. / Zhang, J. / Huang, W. / Wang, Z. / Ding, K. |
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Methods | X-ray diffraction |
Resolution | 2.65 Å |
Structure data | ![]() PDB-8xn7: |
Chemicals | ![]() PDB-1lvt: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Kinase |