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Structure paper

TitleFatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Journal, issue, pagesJ. Cell Biol., Vol. 223, Year 2024
Publish dateMar 27, 2023 (structure data deposition date)
AuthorsFang, X.X. / Wei, P. / Zhao, K. / Sheng, Z.C. / Song, B.L. / Yin, L. / Luo, J.
External linksJ. Cell Biol. / PubMed:38429999
MethodsX-ray diffraction
Resolution2.6 - 2.7 Å
Structure data

PDB-8ivf:
FABP7 complexed with 25-HC
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-8ivl:
FABP7 complexed with Cholesterol
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HC3:
25-HYDROXYCHOLESTEROL / antivirus*YM

ChemComp-HOH:
WATER

ChemComp-CLR:
CHOLESTEROL

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / Complex

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