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Structure paper

TitleIdentification of ss-Glucocerebrosidase Activators for Glucosylceramide hydrolysis.
Journal, issue, pagesChemmedchem, Vol. 19, Page e202300548-e202300548, Year 2024
Publish dateMay 17, 2023 (structure data deposition date)
AuthorsSchulze, M.E.D. / Scholz, D. / Jnoff, E. / Hall, A. / Melin, J. / Sands, Z.A. / Rodriguez, E. / Andre, V.M.
External linksChemmedchem / PubMed:38381042
MethodsX-ray diffraction
Resolution1.75 - 1.83 Å
Structure data

PDB-8p3e:
Crystal structure of glucocerebrosidase in complex with allosteric activator
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-8p41:
Crystal structure of glucocerebrosidase in complex with allosteric activator
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose


ChemComp, No image

ChemComp-WSI:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION


ChemComp, No image

ChemComp-WYC:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Activator / lysosome / glycolipid metabolism

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