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-Structure paper
Title | Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks. |
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Journal, issue, pages | Biochem. J., Vol. 481, Page 437-460, Year 2024 |
Publish date | Jan 27, 2023 (structure data deposition date) |
![]() | Velagapudi, U.K. / Rouleau-Turcotte, E. / Billur, R. / Shao, X. / Patil, M. / Black, B.E. / Pascal, J.M. / Talele, T.T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.7 - 3.8 Å |
Structure data | ![]() PDB-8fyy: ![]() PDB-8fyz: ![]() PDB-8fz1: ![]() PDB-8g0h: |
Chemicals | ![]()
ChemComp-YH0: ![]() ChemComp-DMS: ![]() ChemComp-PEG: ![]() ChemComp-HOH: ![]() ChemComp-CIT: ![]()
ChemComp-YNQ: ![]()
ChemComp-YVB: ![]() ChemComp-EDO: ![]() ChemComp-ZN: |
Source |
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![]() | DNA BINDING PROTEIN/INHIBITOR / PARP / ADP-ribose transferase / DNA BINDING PROTEIN / DNA BINDING PROTEIN-INHIBITOR complex / ADP-ribosyltransferase / DNA binding protein/DNA / DNA break detection / Zinc finger / DNA binding protein-DNA complex |