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Structure paper

TitleCovalent bicyclization of protein complexes yields durable quaternary structures.
Journal, issue, pagesChem, Vol. 10, Page 615-627, Year 2024
Publish dateJun 20, 2023 (structure data deposition date)
AuthorsHutchins, G.H. / Kiehstaller, S. / Poc, P. / Lewis, A.H. / Oh, J. / Sadighi, R. / Pearce, N.M. / Ibrahim, M. / Drienovska, I. / Rijs, A.M. ...Hutchins, G.H. / Kiehstaller, S. / Poc, P. / Lewis, A.H. / Oh, J. / Sadighi, R. / Pearce, N.M. / Ibrahim, M. / Drienovska, I. / Rijs, A.M. / Neubacher, S. / Hennig, S. / Grossmann, T.N.
External linksChem / PubMed:38344167
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-8pi1:
Bicyclic INCYPRO Pseudomonas fluorescens esterase
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZIZ:
N-[2-[3,5-bis[2-(2-iodanylethanoylamino)ethanoyl]-1,3,5-triazinan-1-yl]-2-oxidanylidene-ethyl]-2-iodanyl-ethanamide

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • pseudomonas fluorescens (bacteria)
KeywordsHYDROLASE / stabilization / cyclization / trimer / multimer / esterase

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