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TitleFar-reaching effects of tyrosine64 phosphorylation on Ras revealed with BeF 3 - complexes.
Journal, issue, pagesCommun Chem, Vol. 7, Page 19-19, Year 2024
Publish dateDec 6, 2022 (structure data deposition date)
AuthorsBaumann, P. / Jin, Y.
External linksCommun Chem / PubMed:38297137
MethodsX-ray diffraction
Resolution1.32 - 1.48 Å
Structure data

PDB-8bwg:
HRas (1-166) Y64 phosphorylation
Method: X-RAY DIFFRACTION / Resolution: 1.32 Å

PDB-8cnj:
HRas(1-166) in complex with GDP and BeF3-
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-8cnn:
BeF3 Phospho-HRas GSA complex
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-BEF:
BERYLLIUM TRIFLUORIDE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-ACT:
ACETATE ION

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Small G protein / Ras / Post-translational modification / GTP binding protein / Signalling / cellular signalling / metal fluorides / Ras superfamily / ground state analog

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