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TitleIdentification of small molecule inhibitors of G3BP-driven stress granule formation.
Journal, issue, pagesJ. Cell Biol., Vol. 223, Year 2024
Publish dateNov 20, 2023 (structure data deposition date)
AuthorsFreibaum, B.D. / Messing, J. / Nakamura, H. / Yurtsever, U. / Wu, J. / Kim, H.J. / Hixon, J. / Lemieux, R.M. / Duffner, J. / Huynh, W. ...Freibaum, B.D. / Messing, J. / Nakamura, H. / Yurtsever, U. / Wu, J. / Kim, H.J. / Hixon, J. / Lemieux, R.M. / Duffner, J. / Huynh, W. / Wong, K. / White, M. / Lee, C. / Meyers, R.E. / Parker, R. / Taylor, J.P.
External linksJ. Cell Biol. / PubMed:38284934
MethodsX-ray diffraction
Resolution2.68 Å
Structure data

PDB-8v1l:
Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

Chemicals


ChemComp, No image

ChemComp-Y9M:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Small Molecule / complex / NTF2L / G3BP1 FAZ compound

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