Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization.
Journal, issue, pages	J. Med. Chem., Vol. 67, Page 1758-1782, Year 2024
Publish date	Jul 14, 2023 (structure data deposition date)
Authors	Butini, S. / Grether, U. / Jung, K.M. / Ligresti, A. / Allara, M. / Postmus, A.G.J. / Maramai, S. / Brogi, S. / Papa, A. / Carullo, G. ...Butini, S. / Grether, U. / Jung, K.M. / Ligresti, A. / Allara, M. / Postmus, A.G.J. / Maramai, S. / Brogi, S. / Papa, A. / Carullo, G. / Sykes, D. / Veprintsev, D. / Federico, S. / Grillo, A. / Di Guglielmo, B. / Ramunno, A. / Stevens, A.F. / Heer, D. / Lamponi, S. / Gemma, S. / Benz, J. / Di Marzo, V. / van der Stelt, M. / Piomelli, D. / Campiani, G.
External links	J. Med. Chem. / PubMed:38241614
Methods	X-ray diffraction
Resolution	1.51 - 1.73 Å
Structure data	PDB-8ptc: COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5d Method: X-RAY DIFFRACTION / Resolution: 1.51 Å PDB-8ptq: COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l Method: X-RAY DIFFRACTION / Resolution: 1.55 Å PDB-8ptr: COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5r Method: X-RAY DIFFRACTION / Resolution: 1.73 Å
Chemicals	ChemComp-F28: 4-[(3~{R},4~{S})-2-oxidanylidene-3,4-diphenyl-azetidin-1-yl]piperidine-1-carbaldehyde ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-HOH: WATER ChemComp-EJI: methyl 4-[(2~{S},3~{R})-3-(4-fluorophenyl)-1-(1-methanoylpiperidin-4-yl)-4-oxidanylidene-azetidin-2-yl]benzoate ChemComp-EFH: (3~{R},4~{S})-4-(1,3-benzodioxol-5-yl)-1-[1-(benzotriazol-1-ylcarbonyl)piperidin-4-yl]-3-(3-fluorophenyl)azetidin-2-one
Source	homo sapiens (human)
Keywords	HYDROLASE / ALPHA/BETA HYDROLASE / SERINE ESTERASE;