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TitleStructural basis and selectivity of sulfatinib binding to FGFR and CSF-1R.
Journal, issue, pagesCommun Chem, Vol. 7, Page 3-3, Year 2024
Publish dateJun 5, 2023 (structure data deposition date)
AuthorsLin, Q. / Dai, S. / Qu, L. / Lin, H. / Guo, M. / Wei, H. / Chen, Y. / Chen, X.
External linksCommun Chem / PubMed:38172256
MethodsX-ray diffraction
Resolution1.69 - 1.988 Å
Structure data

PDB-8jmz:
FGFR1 kinase domain with sulfatinib
Method: X-RAY DIFFRACTION / Resolution: 1.988 Å

PDB-8jot:
Crystal structure of CSF-1R kinase domain with sulfatinib
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

Chemicals


ChemComp, No image

ChemComp-UKI:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / Fibroblast growth factor receptor 1 / TRANSFERASE / TRANSFERASE-INHIBITOR complex / sulfatinib / FGFR1 / DFG-out

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