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-Structure paper
Title | Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors. |
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Journal, issue, pages | Bioorg. Chem., Vol. 143, Page 107032-107032, Year 2023 |
Publish date | Apr 21, 2023 (structure data deposition date) |
![]() | Tamhaev, R. / Grosjean, E. / Ahamed, H. / Chebaiki, M. / Rodriguez, F. / Recchia, D. / Degiacomi, G. / Pasca, M.R. / Maveyraud, L. / Mourey, L. / Lherbet, C. |
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Methods | X-ray diffraction |
Resolution | 2.108 Å |
Structure data | ![]() PDB-8otl: |
Chemicals | ![]() ChemComp-NAD: ![]() ChemComp-ACT: ![]() ChemComp-EDO: ![]() ChemComp-VZE: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / enoyl-ACP-reductase type II fatty acid synthase mycolic acids tuberculosis therapeutic target |