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Structure paper

TitleA new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
Journal, issue, pagesPlos Biol., Vol. 21, Page e3002415-e3002415, Year 2023
Publish dateJan 28, 2022 (structure data deposition date)
AuthorsSimmons, H.C. / Watanabe, A. / Oguin Iii, T.H. / Van Itallie, E.S. / Wiehe, K.J. / Sempowski, G.D. / Kuraoka, M. / Kelsoe, G. / McCarthy, K.R.
External linksPlos Biol. / PubMed:38127922
MethodsX-ray diffraction
Resolution3 - 3.6 Å
Structure data

PDB-7trh:
Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7tri:
Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2)
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

Source
  • influenza a virus
  • homo sapiens (human)
  • influenza a virus (a/sydney/5/1997(h3n2))
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / influenza / antibody / neutralizing / IMMUNE SYSTEM / IMMUNE SYSTEM-VIRAL PROTEIN complex

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