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Structure paper

TitleAccurate modeling of peptide-MHC structures with AlphaFold.
Journal, issue, pagesStructure, Vol. 32, Page 228-, Year 2024
Publish dateJun 29, 2023 (structure data deposition date)
AuthorsMikhaylov, V. / Brambley, C.A. / Keller, G.L.J. / Arbuiso, A.G. / Weiss, L.I. / Baker, B.M. / Levine, A.J.
External linksStructure / PubMed:38113889
MethodsX-ray diffraction
Resolution2.081 - 2.87 Å
Structure data

PDB-8tbv:
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Method: X-RAY DIFFRACTION / Resolution: 2.64 Å

PDB-8tbw:
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) peptide KLSHQPVLL
Method: X-RAY DIFFRACTION / Resolution: 2.081 Å

PDB-8u9g:
Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Method: X-RAY DIFFRACTION / Resolution: 2.87 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NO3:
NITRATE ION

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Complex / MHC-I / antigen presentation

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