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Structure paper

TitleStructural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Journal, issue, pagesSci Rep, Vol. 13, Page 22326-22326, Year 2023
Publish dateAug 22, 2023 (structure data deposition date)
AuthorsLee, Y. / Kim, H. / Lee, E. / Hahn, H. / Heo, Y. / Jang, D.M. / Kwak, K. / Kim, H.J. / Kim, H.S.
External linksSci Rep / PubMed:38102161
MethodsX-ray diffraction
Resolution1.39 - 1.51 Å
Structure data

PDB-8khm:
Crystal structure of human methionine aminopeptidase 12 (MAP12) in the unbound form
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

PDB-8khn:
Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two cobalt ions
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-8kho:
Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two Cobalt ions and Methionine
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CO:
Unknown entry

ChemComp-MET:
METHIONINE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Methionine aminopeptidase / Metal-activated proteases / Mitochondrial-targeted protein

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