+Search query
-Structure paper
Title | Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 98, Page 129575-129575, Year 2023 |
Publish date | Sep 14, 2023 (structure data deposition date) |
![]() | Kageji, H. / Momose, T. / Nagamoto, Y. / Togashi, N. / Yasumatsu, I. / Nishikawa, Y. / Kihara, K. / Hiramoto, K. / Minami, M. / Kasanuki, N. ...Kageji, H. / Momose, T. / Nagamoto, Y. / Togashi, N. / Yasumatsu, I. / Nishikawa, Y. / Kihara, K. / Hiramoto, K. / Minami, M. / Kasanuki, N. / Isoyama, T. / Naito, H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.55 Å |
Structure data | ![]() PDB-8wd4: |
Chemicals | ![]() ChemComp-W7W: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
|
![]() | ONCOPROTEIN / EGFR / C797S / Drug Discovery |