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-Structure paper
Title | Epinephrine inhibits PI3K alpha via the Hippo kinases. |
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Journal, issue, pages | Cell Rep, Vol. 42, Page 113535-113535, Year 2023 |
Publish date | Aug 2, 2022 (structure data deposition date) |
Authors | Lin, T.Y. / Ramsamooj, S. / Perrier, T. / Liberatore, K. / Lantier, L. / Vasan, N. / Karukurichi, K. / Hwang, S.K. / Kesicki, E.A. / Kastenhuber, E.R. ...Lin, T.Y. / Ramsamooj, S. / Perrier, T. / Liberatore, K. / Lantier, L. / Vasan, N. / Karukurichi, K. / Hwang, S.K. / Kesicki, E.A. / Kastenhuber, E.R. / Wiederhold, T. / Yaron, T.M. / Huntsman, E.M. / Zhu, M. / Ma, Y. / Paddock, M.N. / Zhang, G. / Hopkins, B.D. / McGuinness, O. / Schwartz, R.E. / Ersoy, B.A. / Cantley, L.C. / Johnson, J.L. / Goncalves, M.D. |
External links | Cell Rep / PubMed:38060450 |
Methods | X-ray diffraction |
Resolution | 2.818 Å |
Structure data | PDB-8am0: |
Chemicals | ChemComp-MWF: ChemComp-EDO: ChemComp-PGE: ChemComp-CL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / lipid kinase / phosphoinositide / 3-kinase / signaling |