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TitleDiscovery of Selective and Orally Available Galectin-1 Inhibitors.
Journal, issue, pagesJ. Med. Chem., Vol. 66, Page 16980-16990, Year 2023
Publish dateMar 24, 2023 (structure data deposition date)
AuthorsZetterberg, F.R. / Diehl, C. / Hakansson, M. / Kahl-Knutson, B. / Leffler, H. / Nilsson, U.J. / Peterson, K. / Roper, J.A. / Slack, R.J.
External linksJ. Med. Chem. / PubMed:38059452
MethodsX-ray diffraction
Resolution1.71 Å
Structure data

PDB-8ojp:
Human galectin 1 in complex with inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

Chemicals


ChemComp, No image

ChemComp-VPZ:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / galectin / ligand / complex / sugar binding

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