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TitleSARS-CoV-2 ORF3a-Mediated NF-kappa B Activation Is Not Dependent on TRAF-Binding Sequence.
Journal, issue, pagesViruses, Vol. 15, Year 2023
Publish dateJun 14, 2023 (structure data deposition date)
AuthorsBusscher, B.M. / Befekadu, H.B. / Liu, Z. / Xiao, T.S.
External linksViruses / PubMed:38005906
MethodsX-ray diffraction
Resolution1.9 - 2.5 Å
Structure data

PDB-8t5p:
SARS-CoV-2 ORF3a peptide in complex with TRAF3 TRAF domain
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-8t5q:
SARS-CoV-2 ORF3a peptide in complex with TRAF2 TRAF domain
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsSIGNALING PROTEIN/VIRAL PROTEIN / signaling protein-viral protein complex

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