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Structure paper

TitleStructural and biochemical insights into NEIL2's preference for abasic sites.
Journal, issue, pagesNucleic Acids Res., Vol. 51, Page 12508-12521, Year 2023
Publish dateJul 14, 2023 (structure data deposition date)
AuthorsEckenroth, B.E. / Bumgarner, J.D. / Matsumoto-Elliott, O. / David, S.S. / Doublie, S.
External linksNucleic Acids Res. / PubMed:37971311
MethodsX-ray diffraction
Resolution2.08 Å
Structure data

PDB-8th9:
Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • monodelphis domestica (gray short-tailed opossum)
  • synthetic construct (others)
KeywordsLYASE / NEIL2 / DNA glycosylase / DNA lyase

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