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TitleSelective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma.
Journal, issue, pagesNat Commun, Vol. 14, Page 7069-7069, Year 2023
Publish dateNov 14, 2022 (structure data deposition date)
AuthorsZhou, L.L. / Zhang, T. / Xue, Y. / Yue, C. / Pan, Y. / Wang, P. / Yang, T. / Li, M. / Zhou, H. / Ding, K. ...Zhou, L.L. / Zhang, T. / Xue, Y. / Yue, C. / Pan, Y. / Wang, P. / Yang, T. / Li, M. / Zhou, H. / Ding, K. / Gan, J. / Ji, H. / Yang, C.G.
External linksNat Commun / PubMed:37923710
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-8hgk:
Crystal structure of human ClpP in complex with ZK53
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZLL:
4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / activator / ZK53 / human ClpP

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