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TitleStructural insights for selective disruption of Beclin 1 binding to Bcl-2.
Journal, issue, pagesCommun Biol, Vol. 6, Page 1080-1080, Year 2023
Publish dateSep 5, 2023 (structure data deposition date)
AuthorsPan, Y.Z. / Liang, Q. / Tomchick, D.R. / De Brabander, J.K. / Rizo, J.
External linksCommun Biol / PubMed:37875561
MethodsNMR (solution)
Structure data

PDB-8u27:
Bcl-2-xL complexed with compound 35
Method: SOLUTION NMR

Chemicals

ChemComp-ULL:
propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / Autophagy / selective inhibition

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