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Structure paper

TitleGuaB3, an overlooked enzyme in cyanobacteria's toolbox that sheds light on IMP dehydrogenase evolution.
Journal, issue, pagesStructure, Vol. 31, Page 1526-1534.e4, Year 2023
Publish dateMay 17, 2023 (structure data deposition date)
AuthorsHernandez-Gomez, A. / Irisarri, I. / Fernandez-Justel, D. / Pelaez, R. / Jimenez, A. / Revuelta, J.L. / Balsera, M. / Buey, R.M.
External linksStructure / PubMed:37875114
MethodsX-ray diffraction
Resolution1.219 - 1.88 Å
Structure data

PDB-8p37:
Structure a catalytically inactive mutant of the IMP dehydrogenase related protein GUAB3 from Synechocystis PCC 6803
Method: X-RAY DIFFRACTION / Resolution: 1.219 Å

PDB-8p4q:
Structure of the IMP dehydrogenase related protein GUAB3 from Synechocystis PCC 6803
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

Chemicals

ChemComp-XMP:
XANTHOSINE-5'-MONOPHOSPHATE

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

ChemComp-IMP:
INOSINIC ACID

Source
  • synechocystis sp. pcc 6803 (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Complex of the enzyme with cofactor and product / IMP dehydrogenase related protein GUAB3 complexed to IMP-XMP

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