EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
ジャーナル・号・ページ	Nat Commun, Vol. 14, Page 6638-6638, Year 2023
掲載日	2023年5月13日 (構造データの登録日)
著者	Jin, S. / Chen, X. / Yang, J. / Ding, J.
リンク	Nat Commun / PubMed:37863926
手法	X線回折
解像度	1.31 - 1.96 Å
構造データ	PDB-8jdb: Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8jdc: Crystal structure of mLDHD in apo form 手法: X-RAY DIFFRACTION / 解像度: 1.696 Å PDB-8jdd: Crystal structure of H405A mLDHD in apo form 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-8jde: Crystal structure of mLDHD in complex with D-lactate 手法: X-RAY DIFFRACTION / 解像度: 1.729 Å PDB-8jdf: Crystal structure of H405A mLDHD in complex with D-lactate 手法: X-RAY DIFFRACTION / 解像度: 1.69 Å PDB-8jdg: Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.31 Å PDB-8jdn: Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid 手法: X-RAY DIFFRACTION / 解像度: 1.56 Å PDB-8jdo: Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-8jdp: Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-8jdq: Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid 手法: X-RAY DIFFRACTION / 解像度: 1.39 Å PDB-8jdr: Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid 手法: X-RAY DIFFRACTION / 解像度: 1.64 Å PDB-8jds: Crystal structure of mLDHD in complex with Pyruvate 手法: X-RAY DIFFRACTION / 解像度: 1.636 Å PDB-8jdt: Crystal structure of mLDHD in complex with 2-ketobutanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-8jdu: Crystal structure of mLDHD in complex with 2-ketovaleric acid 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-8jdv: Crystal structure of mLDHD in complex with 2-ketohexanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-8jdx: Crystal structure of mLDHD in complex with 2-ketoisovaleric acid 手法: X-RAY DIFFRACTION / 解像度: 1.79 Å PDB-8jdy: Crystal structure of mLDHD in complex with 2-ketoisocaproic acid 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-8jdz: Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid 手法: X-RAY DIFFRACTION / 解像度: 1.56 Å
化合物	ChemComp-FAD: FLAVIN-ADENINE DINUCLEOTIDE / FAD / FADYM ChemComp-UIT: (2R)-2-oxidanyloctanoic acid / (2R)-2-ヒドロキシオクタン酸 ChemComp-HOH: WATER ChemComp-MN: Unknown entry ChemComp-LAC: LACTIC ACID / D-乳酸 ChemComp-UCU: (2R)-2-oxidanylbutanoic acid / (R)-2-ヒドロキシ酪酸 ChemComp-UE3: (2R)-2-oxidanylpentanoic acid / (R)-2-ヒドロキシペンタン酸 ChemComp-7N6: (2R)-2-hydroxyhexanoic acid / (R)-2-ヒドロキシヘキサン酸 ChemComp-VAD: DEAMINOHYDROXYVALINE / (R)-2-ヒドロキシ-3-メチルブタン酸 ChemComp-2RH: (2R)-2-hydroxy-4-methylpentanoic acid / (R)-2-ヒドロキシ-4-メチルペンタン酸 ChemComp-UEI: (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid / (2R,3S)-2-ヒドロキシ-3-メチルペンタン酸 ChemComp-PYR: PYRUVIC ACID / ピルビン酸 ChemComp-2KT: 2-KETOBUTYRIC ACID / α-ケト酪酸 ChemComp-69O: 2-oxopentanoic acid / 2-オキソ吉草酸 ChemComp-7N5: 2-Ketohexanoic acid / α-ケトカプロン酸 ChemComp-KIV: 3-METHYL-2-OXOBUTANOIC ACID / α-ケトイソ吉草酸 ChemComp-COI: 2-OXO-4-METHYLPENTANOIC ACID / α-ケトイソカプロン酸 ChemComp-1QQ*: (3S)-3-methyl-2-oxopentanoic acid / α-オキソ-α-デアミノイソロイシン
由来	mus musculus (ハツカネズミ)
キーワード	OXIDOREDUCTASE / D-lactate dehydrogenase / LDHD / 2-hydroxyacid