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-Structure paper
Title | A cell-active cyclic peptide targeting the Nrf2/Keap1 protein-protein interaction. |
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Journal, issue, pages | Chem Sci, Vol. 14, Page 10800-10805, Year 2023 |
Publish date | Aug 1, 2023 (structure data deposition date) |
Authors | Iegre, J. / Krajcovicova, S. / Gunnarsson, A. / Wissler, L. / Kack, H. / Luchniak, A. / Tangefjord, S. / Narjes, F. / Spring, D.R. |
External links | Chem Sci / PubMed:37829032 |
Methods | X-ray diffraction |
Resolution | 1.33 - 1.378 Å |
Structure data | PDB-8q1q: PDB-8q1r: |
Chemicals | ChemComp-SO4: ChemComp-IZS: ChemComp-HOH: ChemComp-NA: |
Source |
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Keywords | LIGASE / Keap1 / cyclic peptide / E3 ligase adaptor / antioxidant response |