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-Structure paper
Title | Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand. |
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Journal, issue, pages | Structure, Vol. 31, Page 1545-, Year 2023 |
Publish date | May 30, 2023 (structure data deposition date) |
![]() | Huber, A.D. / Poudel, S. / Li, Y. / Lin, W. / Wu, J. / Miller, D.J. / Chen, T. |
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Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-8szv: |
Chemicals | ![]() ChemComp-X1D: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / nuclear receptor / transcription factor / metabolism / antibiotic |