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Structure paper

TitleStructural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 105256-105256, Year 2023
Publish dateSep 24, 2022 (structure data deposition date)
AuthorsScaletti, E.R. / Pettersson, P. / Patrick, J. / Shilling, P.J. / Westergren, R.G. / Daley, D.O. / Maler, L. / Widmalm, G. / Stenmark, P.
External linksJ. Biol. Chem. / PubMed:37716703
MethodsX-ray diffraction
Resolution1.95 - 2.2 Å
Structure data

PDB-8b5q:
Crystal Structure of P. aeruginosa WaaG in complex with UMP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-8b5s:
Crystal Structure of P. aeruginosa WaaG in complex with UDP-glucose
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-8b62:
Crystal Structure of P. aeruginosa WaaG in complex with UDP-galactose
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-8b63:
Crystal Structure of P. aeruginosa WaaG in complex with UDP-GalNAc
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-U:
URIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-UPG:
URIDINE-5'-DIPHOSPHATE-GLUCOSE

ChemComp-GDU:
GALACTOSE-URIDINE-5'-DIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-UD2:
URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE

ChemComp-ACT:
ACETATE ION

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsTRANSFERASE / WaaG / glycosyltransferase

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