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TitleCrystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 105228-105228, Year 2023
Publish dateAug 6, 2023 (structure data deposition date)
AuthorsWatson, P.R. / Stollmaier, J.G. / Christianson, D.W.
External linksJ. Biol. Chem. / PubMed:37703993
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-8tq0:
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with (R)-Lipoic Acid
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-RED:
DIHYDROLIPOIC ACID

ChemComp-ZN:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • danio rerio (zebrafish)
KeywordsHYDROLASE/INHIBITOR / Hydrolase / histone deacetylase / inhibitor / metallohydrolase / HYDROLASE-INHIBITOR complex

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